The Hydroxyl at Position C1 of Genipin Is the Active Inhibitory Group that Affects Mitochondrial Uncoupling Protein 2 in Panc-1 Cells
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference38 articles.
1. Enzymic studies on the animal and intestinal bacterial metabolism of geniposide;T Akao;Biol Pharm Bull,1994
2. Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages;W Jeon;Arch Biochem Biophys,2011
3. Genipin inhibits lipopolysaccharide-induced acute systemic inflammation in mice as evidenced by nuclear factor-κB bioluminescent imaging-guided transcriptomic analysis;CC Li;Food Chem Toxicol,2012
4. Genipin selectively inhibits TNF-α-activated VCAM-1 but not ICAM-1 expression by upregulation of PPAR-γ in human endothelial cells;JS Hwa;Korean J Physiol Pharmacol,2011
5. Genipin inhibits mitochondrial uncoupling protein 2 expression and ameliorates podocyte injury in diabetic mice;W Qiu;PLoS One,2012
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