An introduction to the Marburg virus vaccine consortium, MARVAC

Author:

Cross Robert W.,Longini Ira M.,Becker Stephan,Bok Karin,Boucher David,Carroll Miles W.,Díaz Janet V.,Dowling William E.,Draghia-Akli Ruxandra,Duworko James T.,Dye John M.,Egan Michael A.,Fast Patricia,Finan Amy,Finch Courtney,Fleming Thomas R.,Fusco Joan,Geisbert Thomas W.,Griffiths Anthony,Günther Stephan,Hensley Lisa E.,Honko Anna,Hunegnaw Ruth,Jakubik Jocelyn,Ledgerwood Julie,Luhn Kerstin,Matassov Demetrius,Meshulam Jeffrey,Nelson Emily V.,Parks Christopher L.,Rustomjee Roxana,Safronetz David,Schwartz Lauren M.,Smith Dean,Smock Paul,Sow Ydrissa,Spiropoulou Christina F.,Sullivan Nancy J.,Warfield Kelly L.,Wolfe Daniel,Woolsey Courtney,Zahn Roland,Henao-Restrepo Ana María,Muñoz-Fontela César,Marzi AndreaORCID

Abstract

The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine research and development aiming to facilitate a rapid response to this infectious disease threat. Here, we discuss current progress, challenges, and future directions for MARV vaccines.

Funder

National Institute of Allergy and Infectious Diseases, NIH

NIAID/NIH

Deutsches Zentrum für Infektionsforschung

DZIF

NIH

DTRA

Biomedical Advanced Research and Development Authority

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference45 articles.

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3. ISID ProMED. Marburg virus disease–Ghana 2022. 2022 Jul 28. Available from: https://promedmail.org/promed-post/?id=8704707. https://promedmail.org/promed-post/?id=8704676.

4. Filovirus Research: How it Began;W. Slenczka;Curr Top Microbiol Immunol,2017

5. Viral load among patients infected with Marburgvirus in Angola;M Weidmann;J Clin Virol,2007

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