Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

Author:

Comer Ashley L.ORCID,Jinadasa TushareORCID,Sriram BalajiORCID,Phadke Rhushikesh A.,Kretsge Lisa N.,Nguyen Thanh P. H.ORCID,Antognetti Giovanna,Gilbert James P.ORCID,Lee Jungjoon,Newmark Elena R.ORCID,Hausmann Frances S.ORCID,Rosenthal SaraAnn,Liu Kot KevinORCID,Liu Yenyu,Yen William W.ORCID,Dejanovic Borislav,Cruz-Martín AlbertoORCID

Funder

Brain and Behavior Research Foundation

NSF

Boston University Brenton R. Lutz Award

Biogen

Publisher

Public Library of Science (PLoS)

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference72 articles.

1. Schizophrenia;RS Kahn;Nat Rev Dis Primers,2015

2. Altering the course of schizophrenia: progress and perspectives;MJ Millan;Nat Rev Drug Discov,2016

3. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia;JA Lieberman;N Engl J Med,2005

4. Cognitive impairment and functional outcome in schizophrenia and bipolar disorder;MF Green;J Clin Psychiatry,2006

5. Social cognition in schizophrenia;MF Green;Nat Rev Neurosci,2015

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