Leiomodin creates a leaky cap at the pointed end of actin-thin filaments

Author:

Tolkatchev DmitriORCID,Smith Garry E.ORCID,Schultz Lauren E.ORCID,Colpan MertORCID,Helms Gregory L.,Cort John R.ORCID,Gregorio Carol C.,Kostyukova Alla S.ORCID

Funder

National Institutes of Health

National Institute of General Medical Sciences

American Heart Association

National Heart, Lung, and Blood Institute

Publisher

Public Library of Science (PLoS)

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference83 articles.

1. Atomic model of the actin filament;KC Holmes;Nature,1990

2. Structure of the F-actin-tropomyosin complex;J von der Ecken;Nature,2015

3. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy;M Yuen;The Journal of clinical investigation,2014

4. Mutation-specific effects on thin filament length in thin filament myopathy;JM Winter;Annals of neurology,2016

5. Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality;CT Pappas;Proceedings of the National Academy of Sciences of the United States of America,2015

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