Abstract
Smoking and obesity are leading causes of morbidity and mortality worldwide. E-cigarette which was first introduced in 2000s is perceived as an effective alternative to conventional tobacco smoking. Limited knowledge is available regarding the risks and benefits of e-cigarettes. This study systematically reviews the current literature on the effects of e-cigarettes on body weight changes and adipocytes. The search was performed using OVID Medline and Scopus databases and studies meeting the inclusion criteria were independently assessed. This review included all English language, empirical quantitative and qualitative papers that investigated the effects of e-cigarettes on bodyweight or lipid accumulation or adipocytes. Literature searches identified 4965 references. After removing duplicates and screening for eligibility, thirteen references which involve human, in vivo and in vitro studies were reviewed and appraised. High prevalence of e-cigarette was reported in majority of the cross sectional studies conducted among respondent who are obese or overweight. More conclusive findings were identified in in vivo studies with e-cigarette causing weight decrease. However, these observations were not supported by in vitro data. Hence, the effect of e-cigarette on body weight changes warrants further investigations. Well-designed population and molecular studies are needed to further elucidate the role of e-cigarettes in obesity.
Publisher
Public Library of Science (PLoS)
Reference87 articles.
1. Connection of nicotine to diet-induced obesity and non-alcoholic fatty liver disease: Cellular and mechanistic insights;AP Sinha-Hikim;Frontiers in Endocrinology,2017
2. Impact of Carers’ Smoking status on childhood obesity in the Growing Up in Ireland Cohort Study;S Sunday;Int J Environ Res Public Health,2019
3. The effect of smoking on obesity: Evidence from a randomized trial;C Courtemanche;J Health Econ,2018
4. Association between obesity and cigarette smoking: A community-based study;IA Ginawi;J Endocrinol Metab,2016
5. Analysis of factors that determine weight gain during smoking cessation therapy;M Komiyama;PLoS One,2013
Cited by
9 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献