Particulate matter 2.5, metropolitan status, and heart failure outcomes in US counties: A nationwide ecologic analysis

Author:

Chen Edward W.ORCID,Ahmad KhansaORCID,Erqou Sebhat,Wu Wen-ChihORCID

Abstract

The relationship between particulate matter with a diameter of 2.5 micrometers or less (PM2.5) and heart failure (HF) hospitalizations and mortality in the US is unclear. Prior studies are limited to studying the effects of daily PM2.5exposure on HF hospitalizations in specific geographic regions. Because PM2.5can vary by geography, this study examines the effects of annual ambient PM2.5exposure on HF hospitalizations and mortality at a county-level across the US. A cross-sectional analysis of county-level ambient PM2.5concentration, HF hospitalizations, and HF mortality across 3135 US counties nationwide was performed, adjusting for county-level demographics, socioeconomic factors, comorbidities, and healthcare-associated behaviors. There was a moderate correlation between county PM2.5and HF hospitalization among Medicare beneficiaries (r = 0.41) and a weak correlation between county PM2.5and HF mortality (r = 0.08) (p-values < 0.01). After adjustment for various county level covariates, every 1 ug/m3increase in annual PM2.5concentration was associated with an increase of 0.51 HF Hospitalizations/1,000 Medicare Beneficiaries and 0.74 HF deaths/100,000 residents (p-values < 0.05). In addition, the relationship between PM2.5and HF hospitalizations was similar when factoring in metropolitan status of the counties. In conclusion, increased ambient PM2.5concentration level was associated with increased incidence of HF hospitalizations and mortality at the county level across the US. This calls for future studies exploring policies that reduce ambient particulate matter pollution and their downstream effects on potentially improving HF outcomes.

Funder

National Institutes of Health

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference46 articles.

1. Environmental Protection Agency: Particulate Matter (PM) Pollution https://www.epa.gov/pm-pollution/particulate-matter-pm-basics.

2. Effect of exposure to ambient PM2.5 pollution on the risk of respiratory tract diseases: a meta-analysis of cohort studies;Q Liu;J Biomed Res,2017

3. Particulate Matter Air Pollution: Effects on the Cardiovascular System;RB Hamanaka;Front Endocrinol (Lausanne).,2018

4. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association;SS Virani;Circulation,2020

5. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association;EJ Benjamin;Circulation,2019

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The association between PM2.5 and heart failure;International Journal of Cardiology;2024-12

2. Particulate matter 2.5 accelerates aging: Exploring cellular senescence and age-related diseases;Ecotoxicology and Environmental Safety;2024-10

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3