Household factors and the risk of severe COVID-like illness early in the U.S. pandemic

Author:

Nash DenisORCID,Qasmieh Saba,Robertson McKayleeORCID,Rane Madhura,Zimba RebeccaORCID,Kulkarni Sarah G.,Berry AmandaORCID,You William,Mirzayi ChloeORCID,Westmoreland Drew,Parcesepe Angela,Waldron Levi,Kochhar Shivani,Maroko Andrew R.,Grov Christian,

Abstract

Objective To investigate the role of children in the home and household crowding as risk factors for severe COVID-19 disease. Methods We used interview data from 6,831 U.S. adults screened for the Communities, Households and SARS/CoV-2 Epidemiology (CHASING) COVID Cohort Study in April 2020. Results In logistic regression models, the adjusted odds ratio [aOR] of hospitalization due to COVID-19 for having (versus not having) children in the home was 10.5 (95% CI:5.7–19.1) among study participants living in multi-unit dwellings and 2.2 (95% CI:1.2–6.5) among those living in single unit dwellings. Among participants living in multi-unit dwellings, the aOR for COVID-19 hospitalization among participants with more than 4 persons in their household (versus 1 person) was 2.5 (95% CI:1.0–6.1), and 0.8 (95% CI:0.15–4.1) among those living in single unit dwellings. Conclusion Early in the US SARS-CoV-2 pandemic, certain household exposures likely increased the risk of both SARS-CoV-2 acquisition and the risk of severe COVID-19 disease.

Funder

National Institute of Allergy and Infectious Diseases

City University of New York

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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