Nitrogen gas produces less behavioural and neurophysiological excitation than carbon dioxide in mice undergoing euthanasia

Author:

Detotto Carlotta,Isler Sarah,Wehrle Martin,Vyssotski Alexei L.,Bettschart-Wolfensberger RegulaORCID,Gent Thomas C.ORCID

Funder

Bundesamt für Lebensmittelsicherheit und Veterinärwesen

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference52 articles.

1. Report of the ACLAM Task Force on Rodent Euthanasia;J Artwohl;J Am Assoc Lab Anim Sci,2006

2. Euthanasia using gaseous agents in laboratory rodents;AM Valentim;Lab Anim,2015

3. Humane and practical implications of using carbon dioxide mixed with oxygen for anesthesia or euthanasia of rats;PJ Danneman;Lab Anim Sci,1997

4. Carbon dioxide for euthanasia: concerns regarding pain and distress, with special reference to mice and rats;KM Conlee;Lab Anim,2005

5. Sedation or inhalant anesthesia before euthanasia with CO2 does not reduce behavioral or physiologic signs of pain and stress in mice;H Valentine;J Am Assoc Lab Anim Sci,2012

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