Site-specific PEGylation of micro-plasmin for improved thrombolytic therapy through engineering enhanced resistance against serpin mediated inhibition
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference78 articles.
1. Basic and clinical aspects of fibrinolysis and thrombolysis;D Collen;Blood,1991
2. Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits;PA Lapchak;Stroke,2002
3. Safety evaluation of a recombinant plasmin derivative lacking kringles 2–5 and rt-PA in a rat model of transient ischemic stroke;RC Crumrine;Exp Transl Stroke Med,2012
4. The evolution of recombinant thrombolytics: Current status and future directions;Khasa YP Adivitiya;Bioengineered,2017
5. Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential;VJ Marder;J Thromb Haemost,2010
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