Nontherapeutic equivalence of a generic product of imipenem-cilastatin is caused more by chemical instability of the active pharmaceutical ingredient (imipenem) than by its substandard amount of cilastatin-Reference-Cited by-同舟云学术

Nontherapeutic equivalence of a generic product of imipenem-cilastatin is caused more by chemical instability of the active pharmaceutical ingredient (imipenem) than by its substandard amount of cilastatin

Published:2019-02-06 Issue:2 Volume:14 Page:e0211096
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Agudelo Maria^ORCID,Rodriguez Carlos A.,Zuluaga Andres F.,Vesga Omar

Funder

Fundación Cientifica Rodrigo Vesga Meneses

Universidad de Antioquia

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference44 articles.

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3. Generic vancomycin products fail in vivo despite being pharmaceutical equivalents of the innovator;O Vesga;Antimicrob Agents Chemother,2010

4. Even apparently insignificant chemical deviations among bioequivalent generic antibiotics can lead to therapeutic nonequivalence: the case of meropenem;M Agudelo;Antimicrob Agents Chemother,2014

5. Pharmacodynamics of nine generic products of amikacin compared with the innovator in the neutropenic mouse thigh infection model;AF Zuluaga;BMC Res Notes,2015

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