First-in-human Phase I studies of PRS-080#22, a hepcidin antagonist, in healthy volunteers and patients with chronic kidney disease undergoing hemodialysis

Author:

Renders Lutz,Budde Klemens,Rosenberger Christian,van Swelm Rachel,Swinkels Dorine,Dellanna Frank,Feuerer Werner,Wen Ming,Erley Christiane,Bader Birgit,Sommerer Claudia,Schaier Matthias,Meurer KarolineORCID,Matis LouisORCID

Funder

Eurocalin fund

Pieris Pharmaceuticals GmbH

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference36 articles.

1. Prevalence of Anemia in Chronic Kidney Disease in the United States;ME Stauffer;PLoS One,2014

2. National Kidney Foundation KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease;Kidney International Suppl

3. Acute injury with intravenous iron and concerns regarding long-term safety;K Bishu;Clin J Am Soc Nephrol,2006

4. Dialysis Advisory Group of the American Society of Nephrology Considerations and challenges in defining optimal iron utilization in hemodialysis;DM Charytan;J Am Soc Nephrol,2015

5. Hemodialysis-associated hemosiderosis in the era of erythropoiesis-stimulating agents: a MRI study;G Rostoker;Am J Med,2012

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