Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease
Author:
Funder
National Institute of Mental Health
National Institute on Aging
U.S. Department of Veterans Affairs
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference75 articles.
1. Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock;TP Burris;Mol Endocrinol,2008
2. Characterization of the core mammalian clock component, NPAS2, as a REV-ERBa/RORa target gene;C Crumbley;J Biol Chem,2010
3. Direct regulation of CLOCK expression by REV-ERB;C Crumbley;PLoS One,2011
4. The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator;N Preitner;Cell,2002
5. Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β;H Cho;Nature,2012
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