Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway-Reference-Cited by-同舟云学术

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Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway

Published:2019-09-26 Issue:9 Volume:14 Page:e0215886
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Li Yongli,Huang Tengfei,Fu Yun,Wang Tingting,Zhao Tiesuo,Guo Sheng,Sun Yanjie,Yang Yun,Li Changzheng^ORCID

Funder

National Natural Science Foundation of China

Science and Technology Department of Henan Province

Sanquan College of Xinxiang Medical University

the Key Research Project Funding Program of Higher Educational Institutions of Henan Province

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference69 articles.

1. Human DNA topoisomerase I: relaxation, roles, and damage control;JB Leppard;Chromosoma,2005

2. DNA topoisomerases: harnessing and constraining energy to govern chromosome topology;AJ Schoeffler;Q Rev Biophys,2008

3. Podophyllotoxin derivatives: A patent review (2012–2014).;A Kamal;Expert Opin Ther Pat,2015

4. Chemoinduction of cytotoxic selectivity in Podophyllotoxin-related lignans;MA Castro;Phytochem Rev,2003

5. Design and synthesis of the novel DNA topoisomerase II inhibitors: Esterification and amination substituted 4’-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways;L Xiao;Eur J Med Chem,2014

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