Structure-based inhibitory peptide design targeting peptide-substrate binding site in EGFR tyrosine kinase
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference42 articles.
1. Molecular dynamics of the asymmetric dimers of EGFR: Simulations on the active and inactive conformations of the kinase domain;N Songtawee;Journal of Molecular Graphics and Modelling,2015
2. Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization;Y Shan;Cell,2012
3. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6;E Park;Nature Structural and Molecular Biology,2015
4. ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors;R Roskoski Jr;Pharmacological research,2014
5. Mechanism for activation of mutated epidermal growth factor receptors in lung cancer;MR Brewer;Proceedings of the National Academy of Sciences,2013
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