Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model
Author:
Funder
Directorate for Biological Sciences
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference61 articles.
1. Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1;HT Orr;Nat Genet,1993
2. Regulation of ataxin-1 phosphorylation and its impact on biology;S Lagalwar;Methods Mol Biol,2013
3. RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1;J Park;Nature,2013
4. Phosphorylation of ATXN1 at Ser776 in the cerebellum;ND Jorgensen;J Neurochem,2009
5. Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1;J Lim;Nature,2008
Cited by 28 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Polyglutamine disorders: Pathogenesis and potential drug interventions;Life Sciences;2024-05
2. New Perspectives for Antihypertensive Sartans as Components of Co-crystals and Co-amorphous Solids with Improved Properties and Multipurpose Activity;Molecular Pharmaceutics;2023-12-18
3. HD and SCA1: Tales from two 30-year journeys since gene discovery;Neuron;2023-11
4. Advances in cerebellar disorders: pre-clinical models, therapeutic targets, and challenges;Expert Opinion on Therapeutic Targets;2023-10-03
5. The complexities of investigating mitochondria dynamics in multiple sclerosis and mouse models of MS;Frontiers in Neuroscience;2023-07-25
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3