Overcoming the Refractory Expression of Secreted Recombinant Proteins in Mammalian Cells through Modification of the Signal Peptide and Adjacent Amino Acids-Reference-Cited by-同舟云学术

Overcoming the Refractory Expression of Secreted Recombinant Proteins in Mammalian Cells through Modification of the Signal Peptide and Adjacent Amino Acids

Published:2016-05-19 Issue:5 Volume:11 Page:e0155340
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Güler-Gane Gülin,Kidd Sara,Sridharan Sudharsan,Vaughan Tristan J.,Wilkinson Trevor C. I.,Tigue Natalie J.^ORCID

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference25 articles.

1. Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells;A Berlec;J Ind Microbiol Biotechnol,2013

2. Production of recombinant protein therapeutics in cultivated mammalian cells;FM Wurm;Nat Biotechnol,2004

3. Design of Experiment in CHO and HEK transient transfection condition optimization;F Bollin;Protein Expr Purif,2011

4. Regulation of gene expression by alternative promoters;TAY Ayoubi;FASEB J,1996

5. Codon optimization for high-level expression of human erythropoietin (EPO) in mammalian cells;CH Kim;Gene,1997

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