Multiplex Detection of Rare Mutations by Picoliter Droplet Based Digital PCR: Sensitivity and Specificity Considerations

Author:

Zonta Eleonora,Garlan Fanny,Pécuchet Nicolas,Perez-Toralla Karla,Caen Ouriel,Milbury Coren,Didelot Audrey,Fabre Elizabeth,Blons Hélène,Laurent-Puig Pierre,Taly Valérie

Funder

INSERM

Institut National de la Santé et de la Recherche Médicale

Ministère de l'Enseignement Supérieur et de la Recherche

Université Paris-Descartes

Centre National de la Recherche Scientifique (CNRS)

Agence Nationale de la Recherche

SIRIC CARPEM

Cancéropôle Île-de-France

Servier Foundation

Merieux institute

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference38 articles.

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4. Detecting biomarkers with microdroplet technology;V Taly;Trends Mol Med,2012

5. Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy;P Laurent-Puig;Clin Cancer Res,2015

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