Pharmacophore Modeling and Virtual Screening for the Discovery of New type 4 cAMP Phosphodiesterase (PDE4) Inhibitors

Author:

Niu Miaomiao,Dong Fenggong,Tang Shi,Fida Guissi,Qin Jingyi,Qiu Jiadan,Liu Kangbo,Gao Weidong,Gu Yueqing

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference18 articles.

1. Phosphodiesterase 4 and Its Inhibitors in Inflammatory Diseases;SL Jin;Chang Gung Med J,2012

2. Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease;BJ Lipworth;Lancet,2005

3. First dual M3 antagonists-PDE4 inhibitors: synthesis and SAR of 4,6-diaminopyrimidine derivatives;L Provins;Bioorg Med Chem Lett,2006

4. Highly potent PDE4 inhibitors with therapeutic potential;H Ochiai;Bioorg Med Chem,2004

5. Orally active PDE4 inhibitor with therapeutic potential;H Ochiai;Eur J Med Chem,2004

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