Quercetin Enhances the Antitumor Activity of Trichostatin A through Upregulation of p53 Protein Expression In Vitro and In Vivo

Author:

Chan Shu-Ting,Yang Nae-Cherng,Huang Chin-Shiu,Liao Jiunn-Wang,Yeh Shu-Lan

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference47 articles.

1. Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). J Biol Chem;C Henderson,2003

2. Prospects: histone deacetylase inhibitors;M Dokmanovic;J Cell Biochem,2005

3. Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation;SK Seo;J Thorac Oncol,2011

4. Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway;HR Kim;Exp Mol Med,2006

5. The HDAC inhibitor trichostatin A inhibits growth of small cell lung cancer cells;CS Platta;J Surg Res,2007

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