Predictive and Prognostic Impact of TP53 Mutations and MDM2 Promoter Genotype in Primary Breast Cancer Patients Treated with Epirubicin or Paclitaxel

Author:

Chrisanthar Ranjan,Knappskog Stian,Løkkevik Erik,Anker Gun,Østenstad Bjørn,Lundgren Steinar,Risberg Terje,Mjaaland Ingvil,Skjønsberg Gudbrand,Aas Turid,Schlichting Ellen,Fjösne Hans E.,Nysted Arne,Lillehaug Johan Richard,Lønning Per Eystein

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference32 articles.

1. TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer.;S Geisler;Clin Cancer Res,2003

2. Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer.;S Geisler;Cancer Res,2001

3. CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer.;R Chrisanthar;PLoS One,2008

4. TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients.;D Kandioler-Eckersberger;Clin Cancer Res,2000

5. p53-independent apoptosis induced by paclitaxel through an indirect mechanism.;JS Lanni;Proc Natl Acad Sci U S A,1997

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