The C-Terminal TDP-43 Fragments Have a High Aggregation Propensity and Harm Neurons by a Dominant-Negative Mechanism

Author:

Yang Chunxing,Tan Weijia,Whittle Catheryne,Qiu Linghua,Cao Lucheng,Akbarian Schahram,Xu Zuoshang

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference53 articles.

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2. Structural diversity and functional implications of the eukaryotic TDP gene family.;HY Wang;Genomics,2004

3. Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis.;BC Kraemer;Acta Neuropathol,2010

4. TDP-43 is a developmentally-regulated protein essential for early embryonic development.;CF Sephton;Journal of Biological Chemistry,2010

5. TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis.;LS Wu;Genesis,2010

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