Applying Ligands Profiling Using Multiple Extended Electron Distribution Based Field Templates and Feature Trees Similarity Searching in the Discovery of New Generation of Urea-Based Antineoplastic Kinase Inhibitors

Author:

Dokla Eman M.,Mahmoud Amr H.,Elsayed Mohamed S. A.,El-Khatib Ahmed H.,Linscheid Michael W.,Abouzid Khaled A.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference60 articles.

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2. Protein kinase inhibitors from the urea class;J Dumas;Curr Opin Drug Discovery Dev,2002

3. Recent developments in the discovery of protein kinase inhibitors from the urea class;J Dumas;Curr Opin Drug Discovery Dev,2004

4. A small molecule-kinase interaction map for clinical kinase inhibitors;MA Fabian;Nat Biotechnol,2005

5. A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases;O Fedorov;Proc Natl Acad Sci,2007

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