A C1173T Dimorphism in the VKORC1 Gene Determines Coumarin Sensitivity and Bleeding Risk
Author:
Publisher
Public Library of Science (PLoS)
Subject
General Medicine
Reference9 articles.
1. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2. Identification of the gene for vitamin K epoxide reductase
3. Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity
4. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
5. Effect ofVKORC1Haplotypes on Transcriptional Regulation and Warfarin Dose
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