Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance

Author:

Yuzefovych Larysa V.,Pastukh Viktor M.,Ruchko Mykhaylo V.,Simmons Jon D.,Richards William O.,Rachek Lyudmila I.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference48 articles.

1. Inflammatory mechanisms in obesity;MF Gregor;Annu Rev Immunol,2011

2. Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice;C Bonnard;J Clin Invest,2008

3. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans;EJ Anderson;J Clin Invest,2009

4. Insulin resistance is a cellular antioxidant defense mechanism;KL Hoehn;Proc Natl Acad Sci U S A,2009

5. Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria;LI Rachek;J Biol Chem,2002

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