Transient pentameric IgM fulfill biological function—Effect of expression host and transfection on IgM properties

Author:

Hennicke Julia,Schwaigerlehner Linda,Grünwald-Gruber Clemens,Bally Isabelle,Ling Wai Li,Thielens Nicole,Reiser Jean-Baptiste,Kunert RenateORCID

Funder

Austrian Science Fund

ANR C1qEffero grant

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference38 articles.

1. Evaluating the bottlenecks of recombinant IgM production in mammalian cells;V Chromikova;Cytotechnology,2015

2. Recombinant human hexamer-dominant IgM monoclonal antibody to ganglioside GM3 for treatment of melanoma;Y Azuma;Clin Cancer Res,2007

3. High level expression of functional human IgMs in human PER.C6® cells;A Tchoudakova;MAbs,2009

4. A comparative characterization of dipentameric (IgM)2 and pentameric IgM species present in preparations of a monoclonal IgM for therapeutic use;M Tarköy;J Pharm Biomed Anal,2010

5. Quality control in protein biogenesis: thiol-mediated retention monitors the redox state of proteins in the endoplasmic reticulum;JW Brewer;J Cell Sci,1996

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