Pharmacokinetic/pharmacodynamic integration and modelling of florfenicol for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida

Author:

Dorey Lucy,Pelligand Ludovic,Cheng Zhangrui,Lees Peter

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference20 articles.

1. Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization;EI Nielsen,2011

2. Dosing regimen matters: the importance of early intervention and rapid attainment of the pharmacokinetic/pharmacodynamic target;MN Martinez,2012

3. Pharmacokinetic-Pharmacodynamic Modeling of Antibacterial Drugs;EI Nielsen,2013

4. Pharmacokinetic-Pharmacodynamic (PK-PD) modelling and the rational selection of dosage regimes for the prudent use of antimicrobial drugs;MG Papich,2014

5. Use of Monte Carlo simulation to determine pharmacodynamic cutoffs of amoxicillin to establish a breakpoint for antimicrobial susceptibility testing in pigs;JF Rey,2014

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