NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease

Author:

Field Joshua J.ORCID,Majerus Elaine,Ataga Kenneth I.,Vichinsky Elliot P.,Schaub Robert,Mashal Robert,Nathan David G.

Funder

NKT Therapeutics Inc.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference44 articles.

1. Mortality in sickle cell disease. Life expectancy and risk factors for early death;OS Platt,1994

2. Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology;D Zhang,2016

3. Can selectin and iNKT cell therapies meet the needs of people with sickle cell disease?;JJ Field;Hematology Am Soc Hematol Educ Program,2015

4. Invariant natural killer T cells: bridging innate and adaptive immunity;L Van Kaer,2011

5. Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation;M Salio,2007

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