Abstract
This study addressed enamel demineralization, a common complication in fixed orthodontic treatment, by evaluating a novel orthodontic adhesive with DMAHDM-PCL composite fibers. These fibers, produced through electrospinning, were incorporated into orthodontic adhesive to create experimental formulations at different concentrations and a control group. The study assessed antimicrobial properties, biosafety, and mechanical characteristics. New orthodontic adhesive exhibited significant bacteriostatic effects, reducing bacterial biofilm activity and concentrations. Incorporating 1% and 3% DMAHDM-PCL did not affect cytocompatibility. Animal tests confirmed no inflammatory irritation. Shear bond strength and adhesive residual index results indicated that antimicrobial fibers didn’t impact bonding ability. In conclusion, orthodontic adhesives with 3% DMAHDM-PCL fibers are potential antimicrobial bonding materials, offering a comprehensive solution to enamel demineralization in orthodontic patients.
Funder
Qingdao Key Health Discipline Development Fund
Qingdao Clinical Research Center for Oral Diseases
Publisher
Public Library of Science (PLoS)
Reference46 articles.
1. No differences important to patients between orthodontic treatment with customized fixed appliances and conventional appliances;R. Brignardello-Petersen;Journal of the American Dental Association (1939),2017
2. Treatment outcome with orthodontic aligners and fixed appliances: a systematic review with meta-analyses;SN Papageorgiou;European journal of orthodontics,2020
3. A contemporary review of white spot lesions in orthodontics;GC Heymann;Journal of esthetic and restorative dentistry: official publication of the American Academy of Esthetic Dentistry,2013
4. Resin infiltration of enamel white spot lesions: An ultramorphological analysis;J. Perdigão;Journal of esthetic and restorative dentistry: official publication of the American Academy of Esthetic Dentistry,2020
5. Development of white spot lesions during orthodontic treatment: perceptions of patients, parents, orthodontists, and general dentists;BJ Maxfield;American journal of orthodontics and dentofacial orthopedics: official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics,2012