Degradation of HIF-1alpha under Hypoxia Combined with Induction of Hsp90 Polyubiquitination in Cancer Cells by Hypericin: a Unique Cancer Therapy-Reference-Cited by-同舟云学术

Degradation of HIF-1alpha under Hypoxia Combined with Induction of Hsp90 Polyubiquitination in Cancer Cells by Hypericin: a Unique Cancer Therapy

Published:2011-09-19 Issue:9 Volume:6 Page:e22849
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Barliya Tilda,Mandel Mathilda,Livnat Tami,Weinberger Dov,Lavie Gad

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference44 articles.

1. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit.;LE Huang;J Biol Chem,1996

2. Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction.;E Minet;FEBS Lett,1999

3. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.;NJ Mabjeesh;Cancer Res,2002

4. Angiogenesis in cancer, vascular, rheumatoid and other disease.;J Falkman;Nat Med,1995

5. The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase.;HJ Ochel;Mol Genet Metab,1999

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