Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS – A Novel Therapeutic Opportunity-Reference-Cited by-同舟云学术

Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS – A Novel Therapeutic Opportunity

Published:2015-07-15 Issue:7 Volume:10 Page:e0132011
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Winstedt Lena,Järnum Sofia,Nordahl Emma Andersson,Olsson Andreas,Runström Anna,Bockermann Robert,Karlsson Christofer,Malmström Johan,Palmgren Gabriella Samuelsson,Malmqvist Ulf,Björck Lars,Kjellman Christian

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference29 articles.

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2. The global burden of group A streptococcal diseases;JR Carapetis;Lancet Infect Dis,2005

3. Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG;K Wenig;Proc Natl Acad Sci U S A,2004

4. Enzymatic characterization of the streptococcal endopeptidase, IdeS, reveals that it is a cysteine protease with strict specificity for IgG cleavage due to exosite binding;B Vincents;Biochemistry,2004

5. IdeS: a bacterial proteolytic enzyme with therapeutic potential;BP Johansson;PLoS One,2008

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