Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects

Author:

Singh Shantanu,Wu Xiaoyun,Ljosa Vebjorn,Bray Mark-Anthony,Piccioni Federica,Root David E.,Doench John G.,Boehm Jesse S.,Carpenter Anne E.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference60 articles.

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2. Cell-based genomic screening: elucidating virus-host interactions;D Panda;Curr Opin Virol,2012

3. RNAi screening comes of age: improved techniques and complementary approaches;SE Mohr;Nature Publishing Group,2014

4. Vigilance and validation: Keys to success in RNAi screening;FD Sigoillot;ACS Chem Biol,2011

5. Minimizing the risk of reporting false positives in large-scale RNAi screens;CJ Echeverri;Nat Meth,2006

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