In Vitro Glycoengineering of IgG1 and Its Effect on Fc Receptor Binding and ADCC Activity

Author:

Thomann Marco,Schlothauer Tilman,Dashivets Tetyana,Malik Sebastian,Avenal Cecile,Bulau Patrick,Rüger Petra,Reusch Dietmar

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference36 articles.

1. Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action;R Jefferis;Trends in pharmacological sciences,2009

2. Effects of cell culture conditions on antibody N-linked glycosylation-what affects high mannose 5 glycoform;E Pacis;Biotechnol Bioeng,2011

3. Effect of culture temperature on erythropoietin production and glycosylation in a perfusion culture of recombinant CHO cells;WS Ahn;Biotechnol Bioeng,2008

4. Galactosylation variations in marketed therapeutic antibodies;TS Raju;MAbs,2012

5. Acceptable changes in quality attributes of glycosylated biopharmaceuticals;M Schiestl;Nat.Biotechnol,2011

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