Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia-Reference-Cited by-同舟云学术

Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia

Published:2015-08-28 Issue:8 Volume:10 Page:e0136746
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Shi Fangfang,Len Yamei,Gong Yuping,Shi Rui,Yang Xi,Naren Duolan,Yan Tianyou

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference32 articles.

1. Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer;F Pettersson;Clin Cancer Res,2011

2. eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival;JR Graff;Cancer Res,2009

3. Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin;S Assouline;Blood,2009

4. Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap;A Kentsis;Proc Natl Acad Sci U S A,2004

5. Inhibition of eIF4E phosphorylation reduces cell growth and proliferation in primary central nervous system lymphoma cells;D Muta;J Neurooncol,2011

Cited by 37 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. miR-483-5p orchestrates the initiation of protein synthesis by facilitating the decrease in phosphorylated Ser209eIF4E and 4E-BP1 levels;Scientific Reports;2024-02-20

2. Viral Airway Injury Promotes Cell Engraftment in an In Vitro Model of Cystic Fibrosis Cell Therapy;American Journal of Physiology-Lung Cellular and Molecular Physiology;2023-12-27

3. Nonsense mutation suppression is enhanced by targeting different stages of the protein synthesis process;PLOS Biology;2023-11-09

4. The eukaryotic translation initiation factor eIF4E unexpectedly acts in splicing thereby coupling mRNA processing with translation;BioEssays;2023-11-05

5. Biological functions and research progress of eIF4E;Frontiers in Oncology;2023-08-03