Early childhood general anesthesia exposure associated with later developmental delay: A national population-based cohort study

Author:

Feng Yu-PinORCID,Yang Tsorng-Shyang,Chung Chi-Hsiang,Chien Wu-Chien,Wong Chih-Shung

Funder

Tri-Service General Hospital

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference35 articles.

1. Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions;M Deng;Br J Anaesth,2014

2. Isoflurane exposure for three hours triggers apoptotic cell death in neonatal macaque brain;KK Noguchi;Br J Anaesth,2017

3. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits;V Jevtovic-Todorovic;J Neurosci Off J Soc Neurosci,2003

4. Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys;MG Paule;Neurotoxicol Teratol,2011

5. Research C for DE and. Drug Safety and Availability—FDA Drug Safety Communication: FDA review results in new warnings about using general anesthetics and sedation drugs in young children and pregnant women. [cited 7 May 2018]. https://www.fda.gov/Drugs%20/DrugSafety/ucm532356.htm

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