Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity

Author:

Bassani-Sternberg MichalORCID,Chong Chloé,Guillaume Philippe,Solleder Marthe,Pak HuiSong,Gannon Philippe O.ORCID,Kandalaft Lana E.,Coukos George,Gfeller DavidORCID

Funder

CADMOS

Publisher

Public Library of Science (PLoS)

Subject

Computational Theory and Mathematics,Cellular and Molecular Neuroscience,Genetics,Molecular Biology,Ecology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics

Reference54 articles.

1. Towards a systems understanding of MHC class I and MHC class II antigen presentation;J Neefjes;Nat Rev Immunol,2011

2. Neoantigens in cancer immunotherapy;TN Schumacher;Science,2015

3. The IPD and IMGT/HLA database: allele variant databases;J Robinson;Nucleic Acids Res,2015

4. The immune epitope database (IEDB) 3.0;R Vita;Nucleic Acids Res,2015

5. The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design;W Fleri;Front Immunol. Frontiers,2017

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