Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis
Author:
Publisher
Public Library of Science (PLoS)
Subject
Computational Theory and Mathematics,Cellular and Molecular Neuroscience,Genetics,Molecular Biology,Ecology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics
Reference60 articles.
1. The problems in scaling adult drug doses to children;TN Johnson;Arch Dis Child,2008
2. Pediatric Dose Selection and Utility of PBPK in Determining Dose;IE Templeton;AAPS J,2018
3. Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction;J Lu;PLoS Comput Biol,2016
4. Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory Acceptance;M. Jamei;Curr Pharmacol Rep,2016
5. The plasma and cerebrospinal fluid pharmacokinetics of sorafenib after intravenous administration in non-human primates;A Kim;Invest New Drugs,2012
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