Quantitative Comparison of Catalytic Mechanisms and Overall Reactions in Convergently Evolved Enzymes: Implications for Classification of Enzyme Function

Author:

Almonacid Daniel E.,Yera Emmanuel R.,Mitchell John B. O.,Babbitt Patricia C.

Publisher

Public Library of Science (PLoS)

Subject

Computational Theory and Mathematics,Cellular and Molecular Neuroscience,Genetics,Molecular Biology,Ecology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics

Reference123 articles.

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2. SCOPEC: a database of protein catalytic domains.;RA George;Bioinformatics,2004

3. Divergent evolution of enzymatic function: mechanistically diverse superfamilies and functionally distinct suprafamilies.;JA Gerlt;Annu Rev Biochem,2001

4. Understanding enzyme superfamilies. Chemistry as the fundamental determinant in the evolution of new catalytic activities.;PC Babbitt;J Biol Chem,1997

5. Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis.;JA Gerlt;Curr Opin Chem Biol,1998

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