Nitrofurans: Revival of an “old” drug class in the fight against antibiotic resistance

Author:

Le Vuong Van HungORCID,Rakonjac JasnaORCID

Funder

Massey University-MBIE PSAF II grant

Donation by Anne and Bryce Carmine

Callaghan PhD Scholarship

School of Fundamental Sciences

Dextra - New Zealand Pharmaceuticals Ltd

Massey University, School of Fundamental Sciences

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference28 articles.

1. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009–2018;OJ Wouters;JAMA,2020

2. Securing new drugs for future generations: The pipeline of antibiotics;J O’Neill;The Review on Antimicrobial Resistance,2015

3. Reviving old antibiotics;U Theuretzbacher;J Antimicrob Chemother,2015

4. Chemotherapeutic properties of prominent nitrofurans;RE Chamberlain;J Antimicrob Chemother,1976

5. Biochemical characterization of NfsA, the Escherichia coli major nitroreductase exhibiting a high amino acid sequence homology to Frp, a Vibrio harveyi flavin oxidoreductase;S Zenno;J Bacteriol,1996

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