Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability

Author:

Olson William J.,Martorelli Di Genova BrunoORCID,Gallego-Lopez GinaORCID,Dawson Anthony R.ORCID,Stevenson David,Amador-Noguez DanielORCID,Knoll Laura J.ORCID

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference51 articles.

1. Toxoplasmosis: A history of clinical observations;LM Weiss;Int J Parasitol,2009

2. Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii;JI MacRae;Cell Host Microbe,2012

3. Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis;M Blume;Proc Natl Acad Sci U S A,2009

4. Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii;A Shukla;Int J Parasitol,2018

5. 1H-NMR spectroscopic study of aerobic glucose metabolism in Toxoplasma gondii harvested from the peritoneal exudate of experimentally infected mice;A Ohsaka;Physiol Chem Phys,1982

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