PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

Author:

Lin Philana Ling,Maiello Pauline,Gideon Hannah P.,Coleman M. TeresaORCID,Cadena Anthony M.,Rodgers Mark A.,Gregg Robert,O’Malley Melanie,Tomko JaimeORCID,Fillmore Daniel,Frye L. James,Rutledge Tara,DiFazio Robert M.,Janssen Christopher,Klein Edwin,Andersen Peter L.,Fortune Sarah M.,Flynn JoAnne L.

Funder

Bill and Melinda Gates Foundation

Otis Childs Trust of the Children's Hospital of Pittsburgh

National Institute of Allergy and Infectious Diseases

NIH T32

National Heart, Lung, and Blood Institute

National Heart, Lung, and Blood Institute (US)

National Science Foundation

Burroughs Wellcome Fund

Ragon Institute TB Initiative

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference28 articles.

1. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies;CE Barry 3rd;Nature reviews Microbiology,2009

2. Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model;PL Lin;Infection and immunity,2009

3. Reactivation of latent tuberculosis in cynomolgus macaques infected with SIV is associated with early peripheral T cell depletion and not virus load;CR Diedrich;PloS one,2010

4. Understanding latent tuberculosis: a moving target;PL Lin;Journal of immunology,2010

5. Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model;PL Lin;Arthritis and rheumatism,2010

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