Structure of the Cladosporium fulvum Avr4 effector in complex with (GlcNAc)6 reveals the ligand-binding mechanism and uncouples its intrinsic function from recognition by the Cf-4 resistance protein

Author:

Hurlburt Nicholas K.ORCID,Chen Li-HungORCID,Stergiopoulos Ioannis,Fisher Andrew J.ORCID

Funder

Foundation for the National Institutes of Health

National Institute of Food and Agriculture

University of California Office of the President

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference45 articles.

1. Fungal effector proteins;I Stergiopoulos;Annual review of phytopathology,2009

2. Plant-Pathogen Effectors: Cellular Probes Interfering with Plant Defenses in Spatial and Temporal Manners;TY Toruno;Annual review of phytopathology,2016

3. The biotrophic fungus Cladosporium fulvum circumvents Cf-4-mediated resistance by producing unstable AVR4 elicitors;MH Joosten;The Plant cell,1997

4. Tomato Cf resistance proteins mediate recognition of cognate homologous effectors from fungi pathogenic on dicots and monocots;I Stergiopoulos;Proceedings of the National Academy of Sciences of the United States of America,2010

5. Cladosporium fulvum Avr4 protects fungal cell walls against hydrolysis by plant chitinases accumulating during infection;HA van den Burg;Molecular plant-microbe interactions: MPMI,2006

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