Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel

Author:

Kashyap Sudhanva S.,Verma SaurabhORCID,Voronin Denis,Lustigman Sara,Kulke Daniel,Robertson Alan P.,Martin Richard J.ORCID

Funder

National Institutes of Health

E A Benbrook Fellowship

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference37 articles.

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2. WHO. Global Progress Towards Elimination 2019. Available from: https://www.who.int/lymphatic_filariasis/global_progress/en/.

3. DNDi. R&D Portfolio Update March 2018: DNDi Filarial diseases programme 2018. Available from: https://www.dndi.org/2018/media-centre/news-views-stories/news/filaria_rnd_status_2018/.

4. Comparison of the in vitro susceptibility to emodepside of microfilariae, third-stage larvae and adult worms of related filarial nematodes;D Kulke;ASTHM, Baltimore, USA,2017

5. DNDi. 2018 Update. 2018. Available from: https://www.dndi.org/diseases-projects/portfolio/emodepside/.

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