Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis

Author:

Morgan Ethan L.ORCID,Macdonald AndrewORCID

Funder

Medical Research Council

Wellcome Trust

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference93 articles.

1. Papillomaviruses and cancer: from basic studies to clinical application;H. Hausen zur;Nat Rev Cancer,2002

2. Human papillomavirus and cervical cancer;EJ Crosbie;Lancet,2013

3. Binding of human papillomavirus 16 E5 to the 16 kDa subunit c (proteolipid) of the vacuolar H+-ATPase can be dissociated from the E5-mediated epidermal growth factor receptor overactivation;MI Rodríguez;Oncogene. Nature Publishing Group,2000

4. Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene;SM Genther Williams;Cancer Res,2005

5. High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors;LF Wetherill;J Virol. American Society for Microbiology,2012

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