Autocatalytic Activation of the Furin Zymogen Requires Removal of the Emerging Enzyme's N-Terminus from the Active Site-Reference-Cited by-同舟云学术

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Autocatalytic Activation of the Furin Zymogen Requires Removal of the Emerging Enzyme's N-Terminus from the Active Site

Published:2009-04-07 Issue:4 Volume:4 Page:e5031
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Gawlik Katarzyna,Shiryaev Sergey A.,Zhu Wenhong,Motamedchaboki Khatereh,Desjardins Roxane,Day Robert,Remacle Albert G.,Stec Boguslaw,Strongin Alex Y.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference38 articles.

1. The activation and physiological functions of the proprotein convertases.;NG Seidah;Int J Biochem Cell Biol,2008

2. Furin at the cutting edge: from protein traffic to embryogenesis and disease.;G Thomas;Nat Rev Mol Cell Biol,2002

3. Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition.;M Fugere;Trends Pharmacol Sci,2005

4. Proprotein convertases: “master switches” in the regulation of tumor growth and progression.;DE Bassi;Mol Carcinog,2005

5. Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.;AM Khatib;Am J Pathol,2002

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