Genetic polymorphisms of the IL6 and NOD2 genes are risk factors for inflammatory reactions in leprosy

Author:

Sales-Marques Carolinne,Cardoso Cynthia Chester,Alvarado-Arnez Lucia Elena,Illaramendi Ximena,Sales Anna Maria,Hacker Mariana de Andréa,Barbosa Mayara Garcia de Mattos,Nery José Augusto da Costa,Pinheiro Roberta Olmo,Sarno Euzenir Nunes,Pacheco Antonio Guilherme,Moraes Milton OzórioORCID

Funder

Conselho Nacional de Desenvolvimento Científico (CNPq)

Fundação de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ)

Departamento de Ciências e Tecnologia, Conselho Nacional de Desenvolvimento Científico, Ministério da Saúde/Tecnologia de Insumos Estratégicos (DECIT/CNPq/MS/SCTIE)

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference55 articles.

1. Leprosy;WJ Britton;Lancet,2004

2. Pentoxifylline decreases in vivo and in vitro tumour necrosis factor-alpha (TNF-alpha) production in lepromatous leprosy patients with erythema nodosum leprosum (ENL);EP Sampaio;Clinical and experimental immunology,1998

3. Anti-inflammatory drugs block cytokine mRNA accumulation in the skin and improve the clinical condition of reactional leprosy patients;MO Moraes;J Invest Dermatol,2000

4. Neutrophils isolated from leprosy patients release TNF-alpha and exhibit accelerated apoptosis in vitro;RB Oliveira;JLeukocBiol,1999

5. Cytokine mRNA expression in leprosy: a possible role for interferon-gamma and interleukin-12 in reactions (RR and ENL);MO Moraes;Scand J Immunol,1999

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