Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme

Author:

Turcano Lorenzo,Battista Theo,De Haro Esther Torrente,Missineo Antonino,Alli Cristina,Paonessa Giacomo,Colotti Gianni,Harper Steven,Fiorillo AnnaritaORCID,Ilari AndreaORCID,Bresciani AlbertoORCID

Funder

CNCCS s.c.a.r.l.

MIUR

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference41 articles.

1. The Dialogue of the Host-Parasite Relationship: Leishmania spp. and Trypanosoma cruzi Infection;CGV de Morais;Biomed Res Int,2015

2. Melarsoprol Resistance in African Trypanosomiasis;AH Fairlamb;Trends Parasitol,2018

3. Contemporary and emerging strategies for eliminating human African trypanosomiasis due to Trypanosoma brucei gambiense: review;P Steinmann;Trop Med Int Health,2015

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