CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM)

Author:

Debnath Anjan,Calvet Claudia M.,Jennings GarethORCID,Zhou WenxuORCID,Aksenov Alexander,Luth Madeline R.ORCID,Abagyan Ruben,Nes W. David,McKerrow James H.,Podust Larissa M.ORCID

Funder

UCSD start-up fund

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference78 articles.

1. Biology and pathogenesis of Naegleria fowleri;R Siddiqui;Acta Trop,2016

2. Infections with free-living amebae;GS Visvesvara;Handb Clin Neurol,2013

3. Origin and evolution of the worldwide distributed pathogenic amoeboflagellate Naegleria fowleri;JF De Jonckheere;Infect Genet Evol,2011

4. Center for Disease Control and Prevention. Naegleria fowleri—Primary Amebic Meningoencephalitis (PAM)—Amebic Encephalitis. Accessed May 8, 2017 [Available from: https://www.cdc.gov/parasites/naegleria/.

5. Genome-wide identification of pathogenicity factors of the free-living amoeba Naegleria fowleri;DC Zysset-Burri;BMC genomics,2014

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