Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease

Author:

Vitelli-Avelar Danielle Marquete,Sathler-Avelar Renato,Mattoso-Barbosa Armanda Moreira,Gouin Nicolas,Perdigão-de-Oliveira Marcelo,Valério-dos-Reis Leydiane,Costa Ronaldo Peres,Elói-Santos Silvana Maria,Gomes Matheus de Souza,Amaral Laurence Rodrigues do,Teixeira-Carvalho Andréa,Martins-Filho Olindo Assis,Dick Edward J.,Hubbard Gene B.,VandeBerg Jane F.,VandeBerg John L.

Funder

Southwest National Primate Research Center-Base Grant

European Community's Seventh Framework Program—Kindred Project

CPqRR/Fundação Oswaldo Cruz (FIOCRUZ)

Fundação de Amparo à Pesquisa de Minas Gerais (FAPEMIG)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference37 articles.

1. Cytokine profiling in Chagas disease: towards understanding the association with infecting Trypanosoma cruzi discrete typing units (a BENEFIT TRIAL sub-study);C Poveda;PLoS One,2014

2. Pathogenesis of Chagas’ disease: parasite persistence and autoimmunity;ARL Teixeira;Clin Microbiol Rev,2011

3. WHO. Chagas disease (American trypanosomiasis) Fact sheet 340. 2015. Available from: http://www.who.int/mediacentre/factsheets/fs340/en/

4. Chagas disease in European countries: the challenge of a surveillance system;L Basile;Euro Surveill,2011

5. Shelter dogs as sentinels for Trypanosoma cruzi transmission across Texas;TD Tenney;Emerg Infect Dis,2014

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