CORONARY MICROVASCULAR DYSFUNCTION IN PATIENTS AFTER URGENT PERCUTANEOUS CORONARY INTERVENTION DUE TO ACUTE CORONARY SYNDROME

Abstract

Background. Possible cause of residual myocardial ischemia after urgent PCI during ACS is coronary microvascular dysfunction. Aim: To study the frequency of coronary microvascular dysfunction in patients who underwent urgent PCI due to ACS. Materials and methods. The study included 38 participants with ACS. These patients underwent urgent PCI. After 28 days patients underwent echocardiography with intravenous dipyridamole. Coronary microvascular dysfunction was determined by an CFR less than 2. Quality of life was measured by the severity of angina using the SF-36 and SAQ questionnaires, respectively. To compare the results of the study, a cohort of 20 patients who underwent elective PCI without coronary microvascular dysfunction (CFR≥2) were selected. Results.About 2/3 of patients had complaints of shortness of breath, as the equivalent of angina pectoris, during routine physical exertion. In 83.3% patients presence of coronary microvascular dysfunction, was proven. Quality of life due to the SAQ and SF-36 questionnaires were significantly lower among patients, who underwent urgent PCI. Conclusion.The results of the work showed that 83.3% of patients after urgent PCI for ACS were diagnosed with coronary microvascular dysfunction.