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N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons

  • Published:2020-10-31 Issue:10 Volume:53 Page:527-532
  • ISSN:1976-670X
  • Container-title:BMB Reports
  • language:en
  • Short-container-title:BMB Rep.

Author:

Yang Seung-Ju1,Han A Reum2,Choi Hye-Rim1,Hwang Kyouk2,Kim Eun-A2,Choi Soo Young3,Cho Sung-Woo2

Affiliation:

1. Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea

2. Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea

3. Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chunchon 24252, Korea

Funder

Ministry of Education

Ministry of Science and ICT, South Korea

University of Ulsan

Publisher

Korean Society for Biochemistry and Molecular Biology - BMB Reports

Subject

Molecular Biology,Biochemistry,General Medicine

Reference34 articles.

1. Blandini F, Greenamyre JT and Nappi G (1996) The role of glutamate in the pathophysiology of Parkinson's disease. Funct Neurol 11, 3-15

2. Excitotoxicity, apoptosis and neuropsychiatric disorders

3. NMDA receptors in clinical neurology: excitatory times ahead

4. Requirement for Superoxide in Excitotoxic Cell Death

5. Oxidative stress and neurodegeneration: where are we now?
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